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Genetics meets proteomics: perspectives for large population-based studies
Nat Rev Genet (2020).
Serum biomarkers associated with baseline clinical severity in young steroid-naïve Duchenne muscular dystrophy boys
(2020) Human Molecular Genetics, ddaa132
Plasma proteomic profile of frailty
(2020) Aging Cell Aug 6;e13193 doi: 10.1111/acel.13193
Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
(2020) Nature Communications 11, Article 15.
Undulating changes in human plasma proteome profiles across the lifespan
(2019) Nat Med 25:1843-1850.
Plasma protein patterns as comprehensive indicators of health
(2019) Nat Med 25:1851-1857.
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus
(2020) Scientific Reports 10, Article number 4462.
A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer.
(2019) Gynecol Oncol 152(3):574-580.
A cross sectional study of two independent cohorts identifies serum biomarkers for facioscapulohumeral muscular dystrophy (FSHD).
(2016) Neuromuscul Disord 26(7): 405-413
A degradation fragment of type X collagen is a real-time marker for bone growth velocity.
(2017) Sci Transl Med 9(419): eaan4669.
A framework for multi-omic prediction of treatment response to biologic therapy for psoriasis.
(2019) J Invest Dermatol 139(1): 100-107
A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations.
(2017) Am J Clin Nutr 105(2): 343-351.
A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic, and phenomic data domains.
(2017) Sci Rep 7: 43238.
A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study.
(2019) Urology. 2019 Jul;129:35-42
A pilot characterization of the human chronobiome.
(2017) Sci Rep 7(1):17141.
A proteome-derived longitudinal pharmacodynamic biomarker for diffuse systemic sclerosis skin.
(2017) J Invest Dermatol 137(1): 62-70.
A proteomic signature that reflects pancreatic beta-cell function.
(2018) PLoS One 13(8): e0202727
A serum protein signature of APOE genotypes in centenarians.
(2019) Aging Cell. :e13023. doi: 10.1111
Activation of inflammatory and pro-thrombotic pathways in acute stress cardiomyopathy.
(2017) Frontiers in Cardiovascular Medicine 4: 49.
Activin type II receptor signaling in cardiac aging and heart failure.
(2019) Sci Transl Med 11(482).
Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array.
(2012) Am J Pathol 180(2): 446-456.
Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.
(2014) Alzheimers Dement 10(6): 724-734.
An evaluation of an aptamer for use as an affinity reagent with MS: PCSK9 as an example protein.
(2016) Bioanalysis 8(15): 1557-1564.
An immune clock of human pregnancy.
(2017) Sci Immunol 2(15):eaan2946.
Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study.
(2018) Genes Nutr 13: 7
Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults.
(2017) JCI Insight. 2017 Oct 5;2(19). pii: 95893
Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism.
(2019) Clin Epigenetics. 2019; 11: 102
Application of an Aptamer-Based Proteomics Assay (SOMAscan™) in Rat Cerebrospinal Fluid.
(2019) Methods Mol Biol. 2044:221-231
Application of large scale aptamer-based proteomic profiling to planned myocardial infarctions.
(2018) Circulation 137(12): 1270-1277.
Application of Proteomics Profiling for Biomarker Discovery in Hypertrophic Cardiomyopathy.
(2019) J Cardiovasc Transl Res. 2019 Dec;12(6):569-579
Aptamer-based multiplexed proteomic technology for biomarker discovery.
(2010) PLoS One 5(12): e15004.
Aptamer-based proteomic profiling reveals novel candidate biomarkers and pathways in cardiovascular disease.
(2016) Circulation 134(4): 270-285
Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis.
(2014) Tuberculosis (Edinb) 94(3): 187-196.
Aptamer-based proteomics identifies mortality-associated serum biomarkers in dialysis-dependent AKI patients.
(2018) Kidney Int Rep 3(5): 1202-1213
Aptamer-based proteomics of serum and plasma in acquired aplastic anemia.
(2018) Exp Hematol 68: 38-50
Aptamer-based search for correlates of plasma and serum water T2: implications for early metabolic dysregulation and metabolic syndrome.
(2018) Biomark Res 6: 28
Aptamers and the RNA world, past and present.
(2012) Cold Spring Harb Perspect Biol 4(3).
Assessing the genetic correlations between blood plasma proteins and osteoporosis: a polygenic risk score analysis.
(2019) Calcif Tissue Int 104(2): 171-181
Assessment of variability in the SOMAscan assay.
(2017) Sci Rep 7(1):14248.
Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts.
(2015) Eur Heart J 36(48): 3426-3434.
Atopic Dermatitis Endotypes Based on Allergen Sensitization, Reactivity to Staphylococcus aureus Antigens, and Underlying Systemic Inflammation.
(2019) J Allergy Clin Immunol Pract. pii: S2213-2198(19)30719-6.
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.
(2017) EMBO Mol Med 9(11): 1504-1520.
Benefit of apabetalone on plasma proteins in renal disease.
(2018) Kidney International Reports 3(3): 711-721
Cancer protein biomarker discovery based on nucleic acid aptamers.
(2019) Int J Biol Macromol. 2019 Jul 1;132:190-202
Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.
(2014) J Alzheimers Dis 38(3): 515-531.
Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice.
(2019) Toxicol Appl Pharmacol 363:164-173
Cerebrospinal fluid biomarkers link toxic astrogliosis and microglial activation to multiple sclerosis severity.
(2018) Mult Scler Relat Disord 28: 34-43
Cerebrospinal fluid protein changes in preeclampsia.
(2018) Hypertension 72(1): 219-226
Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy.
(2019) Diabetes Care. 2019 Jul;42(7):1263-1273
Characterization of the rat cerebrospinal fluid proteome following acute cerebral ischemia using an aptamer-based proteomic technology.
(2018) Sci Rep 8(1): 7899
Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.
(2014) J Biol Chem 289(12): 8706-8719.
Chemically modified interleukin-6 aptamer inhibits development of collagen-induced arthritis in cynomolgus monkeys.
(2016) Nucleic Acid Ther 26(1): 10-19.
Chemotherapy-induced differential cell cycle arrest in B-cell lymphomas affects their sensitivity to Wee1 inhibition.
(2018) Haematologica 103(3): 466-476
Circulating Biomarkers of Testosterone's Anabolic Effects on Fat-Free Mass.
(2019) https://doi.org/10.1210/jc.2019-00505
Circulating proteomic signatures of chronological age.
(2015) J Gerontol A Biol Sci Med Sci 70(7): 809-816.
Classification of prostate cancer using a protease activity nanosensor library.
(2018) Proc Natl Acad Sci U S A 115(36): 8954-8959
Clinical validation of a protein biomarker panel for non-small cell lung cancer.
(2018) J Korean Med Sci 33(53): e342
Co-regulatory networks of human serum proteins link genetics to disease.
(2018) Science 361(6404): 769-773
Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy.
(2018) PLoS One 13(3): e0194225
Complementarity of SOMAscan to LC-MS/MS and RNA-seq for quantitative profiling of human embryonic and mesenchymal stem cells.
(2017) J Proteomics 150: 86-97
Connecting genetic risk to disease end points through the human blood plasma proteome.
(2017) Nat Commun 8: 14357.
Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand.
(2014) J Biol Chem 289(12): 8720-8734.
Cytokines IL-17, TNF and IFN-gamma alter the expression of antimicrobial peptides and proteins disparately: a targeted proteomics analysis using SOMAscan technology.
(2018) Vaccines (Basel) 6(3).
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.
(2018) Hum Mol Genet 27(6): 1106-1121
Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers.
(2013) Diagn Microbiol Infect Dis 76(3): 278-285
Developing clinically relevant biomarkers in inflammatory arthritis: A multiplatform approach for serum candidate protein discovery.
(2016) Proteomics Clin Appl 10(6): 691-698.
Development and characterization of an HPV Type-16 specific modified DNA aptamer for the improvement of potency assays.
(2017) Anal Chem 89(6): 3554-3561.
Development and validation of a protein-based risk score for cardiovascular outcomes among patients with stable coronary heart disease.
(2016) JAMA 315(23): 2532-2541
Development of a protein biomarker panel to detect non-small-cell lung cancer in Korea.
(2017) Clin Lung Cancer 18(2): e99-e107.
Diagnosis and prognosis-review of biomarkers for mesothelioma.
(2017) Ann Transl Med 5(11): 244.
Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational study.
(2016) BMJ Open 6(11): e013324.
Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.
(2018) Int J Obes (Lond) 42(3): 353-362
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
(2019) PLoS Med. 2019 Apr; 16(4): e1002781
Discovery and validation of a six-marker serum protein signature for the diagnosis of active pulmonary tuberculosis.
(2017) J Clin Microbiol 55(10): 3057-3071.
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
(2019) Alzheimers Dement. 5. pii: S1552-5260(19)35118-0
Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy
(2019) Sci Rep. 2019 Aug 21;9(1):12167
Divergent roles for clusterin in lung injury and repair.
(2017) Sci Rep 7(1): 15444.
Downregulation of the complement cascade in vitro, in mice and in patients with cardiovascular disease by the BET protein inhibitor apabetalone (RVX-208).
(2017) J Cardiovasc Transl Res, 10(4): 337-347.
Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool.
(2012) PLoS One 7(10):e46091.
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening.
(2018) Am J Respir Crit Care Med 197(8): 1076-1080
Efficacy of individualised diets in patients with irritable bowel syndrome: a randomised controlled trial.
(2017) BMJ Open Gastro 4(1): e000164.
Elucidating novel serum biomarkers associated with pulmonary tuberculosis treatment.
(2013) PLoS One 8(4): e61002.
Embracing proteins: structural themes in aptamer-protein complexes.
(2016) Curr Opin Struct Biol 36: 122-132.
Endothelial microparticles and systemic complement activation in patients with chronic kidney disease.
(2018) J Am Heart Assoc 7(14): e007818
Exosome swarms eliminate airway pathogens and provide passive epithelial immunoprotection through nitric oxide.
(2019) J Allergy Clin Immunol 143(4):1525-1535 e1521
Expanding the chemistry of DNA for in vitro selection.
(2010) J Am Chem Soc 132(12): 4141-4151.
Fatigue in sjorgen's syndrome: a search for biomarkers and treatment targets.
(2019) Front Immunol 10: 312.
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
(2017) Nat Genet 49(7): 1113-1119.
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome.
(2019) https://doi.org/10.3390/metabo9070122
Fit for the eye: aptamers in ocular disorders.
(2016) Nucleic Acid Ther 26(3): 127-146.
From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay.
(2011) PLoS One 6(10): e26332.
GDF15 is a heart-derived hormone that regulates body growth.
(2017) EMBO Mol Med 9(8): 1150-1164
Genetic architecture of the cardiovascular risk proteome.
(2018) Circulation 137(11): 1158-1172
Genetic associations with micronutrient levels identified in immune and gastrointestinal networks.
(2014) Genes Nutr 9(4): 408
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.
(2018) Nat Commun 9(1): 3268
Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.
(2017) Hum Mol Genet 26(1): 44-51.
Genomic atlas of the human plasma proteome.
(2018) Nature 558: 73-79
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.
(2013) Cell 153(4): 828-839.
Guidelines for CSF Processing and Biobanking: Impact on the Identification and Development of Optimal CSF Protein Biomarkers.
(2019) Methods Mol Biol. 2044:27-50
Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan.
(2018) J Appl Physiol (1985) 125(5): 1646-1659
Harnessing the power of proteomics to assess drug safety and guide clinical trials.
(2018) Circulation 137(10): 1011-1014
High-content affinity-based proteomics: unlocking protein biomarker discovery.
(2010) Expert Rev Mol Diagn 10(8): 1013-1022.
High-resolution molecular discrimination by RNA.
(1994) Science 263(5152): 1425-1429.
High-throughput characterization of blood serum proteomics of IBD patients with respect to aging and genetic factors.
(2017) PLoS Genet 13(1): e1006565
Highly multiplexed proteomic analysis of quantiferon supernatants to identify biomarkers of latent tuberculosis infection.
(2017) J Clin Microbiol 55(2): 391-402.
Highly multiplexed proteomic analysis reveals significant tissue and exosomal coagulation pathway derangement in chronic rhinosinusitis with nasal polyps.
(2018) Int Forum Allergy Rhinol 8(12): 1438-1444
Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.
(2017) Nature 544(7649): 235-239.
Human PAH is characterized by a pattern of lipid-related insulin resistance.
(2019) JCI Insight 4(1).
Identification of definitive serum biomarkers associated with disease activity in primary sjorgen's syndrome.
(2016) Arthritis Res Ther 18(1): 106.
Identification of novel biomarkers to monitor β-cell function and enable early detection of type 2 diabetes risk.
(2017) PLoS One 12(8): e0182932.
Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis.
(2018) Rheumatology (Oxford) 57(10): 1698-1706
Identification of pathway-specific serum biomarkers of response to glucocorticoid and infliximab treatment in children with inflammatory bowel disease.
(2016) Clin Transl Gastroenterol 7(9): e192.
Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan.
(2019) Ann Surg. 2019 Mar 26. doi: 10.1097
Identification of serum protein biomarkers for utrophin based DMD therapy.
(2017) Sci Rep 7: 43697.
Identification of unique proteomic signatures in allergic and non-allergic skin disease.
(2017) Clin Exp Allergy 47(11): 1456-1467
Identifying low-abundance biomarkers: Aptamer-based proteomics potentially enables more sensitive detection in cardiovascular diseases.
(2016) Circulation 134(4): 286-289.
Improved preparation of 2 M triethylammonium bicarbonate.
(2015) Green Chem Lett Rev 8(3-4): 37-39.
Improving assessment of drug safety through proteomics: early detection and mechanistic characterization of the unforeseen harmful effects of torcetrapib.
(2018) Circulation 137(10): 999-1010
Improving probes for super-resolution.
(2018) Nat Methods 15(9): 659-660
Incorporation of Slow Off-Rate Modified Aptamers reagents in single molecule array assays for cytokine detection with ultrahigh sensitivity.
(2016) Anal Chem 88(17): 8385-8389.
Increased cerebrospinal fluid fibrinogen in major depressive disorder.
(2015) Sci Rep 5: 11412.
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation.
(2018) Sci Rep 8(1): 14915
Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides.
(2015) Nucleic Acids Res 43(19): 9107-9122.
Influenza a virus-triggered autophagy decreases the pluripotency of human-induced pluripotent stem cells.
(2019) Cell Death Dis. 2019 May; 10(5): 337
Integrative omics: harnessing the proteome to maximize the potential of the genome.
(2018) Circulation 137(11): 1173-1175
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
(2013) EMBO Rep 14(12): 1120-1126.
Interleukin 1 receptor-like 1 protein (ST2) is a potential biomarker for cardiomyopathy in Duchenne muscular dystrophy.
(2017) Pediatr Cardiol 38(8): 1606-1612.
Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA.
(1997) Nat Struct Biol 4(8): 644-649.
Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma.
(2014) Cancer Chemother Pharmacol 74(4): 739-750.
Joint fluid proteome after anterior cruciate ligament rupture reflects an acute posttraumatic inflammatory and chondrodegenerative state.
(2018) Cartilage. 2018 Jul 1:1947603518790009
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.
(2017) Sci Transl Med 9(417): eaan8462
Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy.
(2015) Proc Natl Acad Sci U S A 112(23): 7153-7158.
Let's get specific: the relationship between specificity and affinity.
(1995) Chem Biol 2(10): 633-638.
Life's simple measures: unlocking the proteome.
(2012) J Mol Biol 422(5):595-606.
Longitudinal protein changes in blood plasma associated with the rate of cognitive decline in Alzheimer's disease.
(2016) J Alzheimers Dis 49(4): 1105-1114.
Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.
(2016) Nat Med 22(8): 897-905.
Measurement of cetuximab and panitumumab-unbound serum EGFR extracellular domain using an assay based on slow off-rate modified aptamer (SOMAmer) reagents.
(2013) PLoS One 8(8): e71703.
Metabolic and proteomic signatures of hypoglycemia in type 2 diabetes.
(2018) Diabetes Obes Metab., Diabetes Obes Metab. 2018 Dec 7. doi: 10.1111
Methylation potential associated with diet, genotype, protein, and metabolite levels in the Delta Obesity Vitamin Study.
(2014) Genes Nutr 9(3): 403.
Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome.
(2018) Proc Natl Acad Sci U S A 115(23): E5390-E5399
Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging.
(2018) Nat Methods 15(9): 685-688
Molecular-based diagnosis of multiple sclerosis and its progressive stage.
(2017) Ann Neurol 82(5): 795-812.
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.
(2018) Nat Commun 9(1): 2755.
Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjogren's syndrome.
(2017) Ann Rheum Dis 76(8): 1458-1466.
Non-helical DNA triplex forms a unique aptamer scaffold for high affinity recognition of nerve growth factor.
(2015) Structure 23(7): 1293-1304.
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
(2018) J Hepatol 68(2): 305-315.
Noninvasive exosomal proteomic biosignatures, including cystatin SN, peroxiredoxin-5, and glycoprotein VI, accurately predict chronic rhinosinusitis with nasal polyps.
(2019) Int Forum Allergy Rhinol 9(2): 177-186
Novel application of aptamer proteomic analysis in cystic fibrosis bronchoalveolar lavage fluid.
(2018) Proteomics Clin Appl: e1800085
Nucleic acid ligands with protein-like side chains: Modified aptamers and their use as diagnostic and therapeutic agents.
(2014) Mol Ther Nucleic Acids 3:e201.
Osteitis is associated with dysregulated pro-osteoblastic activity in patients with nasal polyps.
(2019) Laryngoscope 129(3): E102-E109
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.
(2017) Development 144(6): 1056-1064.
Pharmacokinetic properties of DNA aptamers with base modifications.
(2017) Nucleic Acid Ther 27(6): 345-353.
Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.
(2018) Pharmacol Res 136: 140-150
Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia.
(2019) Obes Surg. 2019 Jul;29(7):2092-2099
Plasma from some cancer patients inhibits adenoviral Ad5f35 vector transduction of dendritic cells.
(2018) Cytotherapy 20(5): 728-739
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.
(2015) Transl Psychiatry 5: e584.
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study.
(2017) Lancet Respir Med 5(9): 717-726
Plasma proteome in multiple sclerosis disease progression.
(2019) Ann Clin Transl Neurol. 2019 Sep;6(9):1582-1594
Plasma proteomic signature of age in healthy humans.
(2018) Aging Cell 17(5): e12799
Plasma proteomics identifies a 'chemokine storm' in idiopathic multicentric Castleman disease.
(2018) Am J Hematol 93(7): 902-912
Potential of high-affinity, Slow Off-Rate Modified Aptamer (SOMAmer) reagents for Mycobacterium tuberculosis proteins as tools for infection models and diagnostic applications.
(2017) J Clin Microbiol 55(10): 3072-3088
Practical synthesis of cytidine-5-carboxamide-modified nucleotide reagents.
(2015) Nucleosides Nucleotides Nucleic Acids 34(3): 180-198.
Probing the virtual proteome to identify novel disease biomarkers.
(2018) Circulation 138(22): 2469-2481
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator.
(2017) Nat Commun 8(1): 2084
Protein signature of lung cancer tissues.
(2012) PLoS One 7(4): e35157.
Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study.
(2018) PLoS One 13(12): e0208042
Proteomic analysis reveals distinctive protein profiles involved in CD8(+) T cell-mediated murine autoimmune cholangitis.
(2018) Cell Mol Immunol 15(8): 756-767
Proteomic profiles associated with early echocardiogram evidence of pulmonary vascular disease in preterm infants.
(2017) Am J Respir Crit Care Med 197(3): 394-397
Proteomic profiles in advanced age-related macular degeneration using an aptamer-based proteomic technology.
(2019) Transl Vis Sci Technol 8(1): 14
Proteomic profiling identifies novel circulating markers associated with bronchiectasis in cystic fibrosis.
(2017) Proteomics Clin Appl 11(9-10).
Proteomic study of hepatocellular carcinoma using a novel modified aptamer-based array (SOMAscan) platform.
(2017) Biochim Biophys Acta 1865(4): 434-443.
Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan‚Ñ¢) platform.
(2014) Mol Cell Proteomics 13(4): 1050-1064.
Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array.
(2016) J Extracell Vesicles 5: 31209.
Proteomics and diagnostics: Let's get specific, again.
(2008) Curr Opin Chem Biol 12(1): 78-85.
Proteomics in gastroparesis: Unique and overlapping protein signatures in diabetic and idiopathic gastroparesis.
(2019) Am J Physiol Gastrointest Liver Physiol. 2019 Sep 4. doi: 10.1152
Proteomics profiling and risk of new-onset atrial fibrillation: Framingham Heart Study.
(2019) J Am Heart Assoc 8(6): e010976
Pulmonary Aptamer Signatures in Children's Interstitial and Diffuse Lung Diseases.
(2019) Am J Respir Crit Care Med. doi: 10.1164
Rapid histochemistry using slow off-rate modified aptamers with anionic competition.
(2011) Appl Immunohistochem Mol Morphol 19(3): 273-278.
readat: an R package for reading and working with SomaLogic ADAT files.
(2016) BMC Bioinformatics 17(1): 201.
Reproducibility and variability of protein analytes measured using a multiplexed modified aptamer assay.
(2019) J Appl Lab Med. 2019 Jul;4(1):30-39
Respiratory mucosal proteome quantification in human influenza infections.
(2016) PLoS One 11(4): e0153674.
Scanning into the future: the promise of SOMAScan technology for kidney disease.
(2018) Kidney Int Rep 3(5): 1020-1022
Selection of aptamers to Neisseria meningitidis and Streptococcus pneumoniae surface specific proteins and affinity assay using thin film AlN resonators.
(2017) Sensors and Actuators B: Chemical 246: 591-596.
Selection of DNA aptamers with two modified bases.
(2017) Proc Natl Acad Sci U S A 114(11): 2898-2903.
SELEX: How it happened and where it will go.
(2015) J Mol Evol 81(5-6): 140-143.
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.
(2017) PLoS Pathog 13(11): e1006687.
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis.
(2018) Arthritis Res Ther 20(1): 185
Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis.
(2018) Steroids 140: 159-166
Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.
(2016) Sci Rep 6: 31727.
Serum proteomic analysis identifies interleukin 16 as a biomarker for clinical response during early treatment of rheumatoid arthritis.
(2016) Cytokine 78: 87-93.
Serum proteomic assessment of the progression of fracture healing.
(2018) J Orthop Res 36(4): 1153-1163
Sexual dimorphism, age, and fat mass are key phenotypic drivers of proteomic signatures.
(2017) J Proteome Res 16(11): 4122-4133.
Six-SOMAmer index relating to immune, protease and angiogenic functions predicts progression in IPF.
(2016) PLoS One 11(8): e0159878.
Slow Off-Rate Modified Aptamer (SOMAmer) as a Novel Reagent in Immunoassay Development for Accurate Soluble Glypican-3 Quantification in Clinical Samples.
(2018) Anal Chem 90(8): 5162-5170
SOMAscan-based proteomic measurements of plasma brain natriuretic peptide are decreased in mild cognitive impairment and in Alzheimer's dementia patients.
(2019) PLoS One. 2019 Feb 14;14(2):e0212261
Specific capture and detection of Staphylococcus aureus with high-affinity modified aptamers to cell surface components.
(2014) Lett Appl Microbiol 59(4): 422-431.
Sperm cell purification from mock forensic swabs using SOMAmerTM affinity reagents.
(2018) Forensic Sci Int Genet 35: 9-13
Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma.
(2018) J Allergy Clin Immunol 141(2): 560-570.
Stability and reproducibility of proteomic profiles measured with an aptamer-based platform.
(2018) Sci Rep 8(1): 8382
Stress Hyperglycemia in Critically Ill Patients: Insight Into Possible Molecular Pathways.
(2019) Front Med (Lausanne). 2019; 6: 54
Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling.
(2017) Nat Commun 8(1): 810.
Systematic selection of modified aptamer pairs for diagnostic sandwich assays.
(2014) Biotechniques 56(3): 125-128, 130, 132-133.
The differential plasma proteome of obese and overweight individuals undergoing a nutritional weight loss and maintenance intervention.
(2018) Proteomics Clin Appl 12(1).
The human placental proteome secreted into the maternal and fetal circulations in normal pregnancy based on 4-vessel sampling.
(2019) FASEB J 33(2):2944-2956
The impact of micronutrient status on health: correlation network analysis to understand the role of micronutrients in metabolic-inflammatory processes regulating homeostasis and phenotypic flexibility.
(2017) Genes Nutr 12: 5.
The impact of the glomerular filtration rate on the human plasma proteome.
(2018) Proteomics Clin Appl 12(3): e1700067
The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology.
(2017) Alzheimers Res Ther 9(1): 31.
The maternal plasma proteome changes as a function of gestational age in normal pregnancy: a longitudinal study.
(2017) Am J Obstet Gynecol 217(1):67 e61-67 e21.
The peripheral blood proteome signature of idiopathic pulmonary fibrosis is distinct from normal and is associated with novel immunological processes.
(2017) Sci Rep 7: 46560.
The prediction of late-onset preeclampsia: Results from a longitudinal proteomics study.
(2017) PLoS One 12(7): e0181468.
The relationship of circulating proteins in early pregnancy with preterm birth.
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