Interactive Publication Viewer


By disorder

By journal

By year:

Filter by year:

Filter by disorder:

Filter by journal:


Genetics meets proteomics: perspectives for large population-based studies
Suhre, K., McCarthy, M.I. & Schwenk, J.M.
Nat Rev Genet (2020).
SomaScan technology
Serum biomarkers associated with baseline clinical severity in young steroid-naïve Duchenne muscular dystrophy boys
Dang, UJ et. al.
(2020) Human Molecular Genetics, ddaa132
Muskuloskeletal, Pediatric disease
Plasma proteomic profile of frailty
Sathyan, S et. al.
(2020) Aging Cell Aug 6;e13193 doi: 10.1111/acel.13193
Undulating changes in human plasma proteome profiles across the lifespan
Lehallier, B et. al.
(2019) Nat Med 25:1843-1850.
Plasma protein patterns as comprehensive indicators of health
Williams, SA et. al.
(2019) Nat Med 25:1851-1857.
Cardiovascular, Metabolic
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus
Smith, MA et. al.
(2020) Scientific Reports 10, Article number 4462.
Immunity, Inflammatory disease
A degradation fragment of type X collagen is a real-time marker for bone growth velocity.
Coghlan, RF et. al.
(2017) Sci Transl Med 9(419): eaan4669.
Osteoporosis Orthopedics
A framework for multi-omic prediction of treatment response to biologic therapy for psoriasis.
Foulkes, AC et. al.
(2019) J Invest Dermatol 139(1): 100-107
A pilot characterization of the human chronobiome.
Skarke, C et. al.
(2017) Sci Rep 7(1):17141.
Metabolic disease
A proteome-derived longitudinal pharmacodynamic biomarker for diffuse systemic sclerosis skin.
Rice, LM et. al.
(2017) J Invest Dermatol 137(1): 62-70.
A proteomic signature that reflects pancreatic beta-cell function.
Curran, AM et. al.
(2018) PLoS One 13(8): e0202727
Metabolic disease
A serum protein signature of APOE genotypes in centenarians.
Sebastiani P, et. al.
(2019) Aging Cell. :e13023. doi: 10.1111
Activation of inflammatory and pro-thrombotic pathways in acute stress cardiomyopathy.
Fitzgibbons, TP et. al.
(2017) Frontiers in Cardiovascular Medicine 4: 49.
Activin type II receptor signaling in cardiac aging and heart failure.
Roh, JD et. al.
(2019) Sci Transl Med 11(482).
Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array.
Baird, GS et. al.
(2012) Am J Pathol 180(2): 446-456.
Aging Neurological
Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.
Sattlecker, M et. al.
(2014) Alzheimers Dement 10(6): 724-734.
An evaluation of an aptamer for use as an affinity reagent with MS: PCSK9 as an example protein.
Gupta, V et. al.
(2016) Bioanalysis 8(15): 1557-1564.
SomaScan technology
An immune clock of human pregnancy.
Aghaeepour, N et. al.
(2017) Sci Immunol 2(15):eaan2946.
Immunity Reproductive biology
Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults.
Spitsin, S et. al.
(2017) JCI Insight. 2017 Oct 5;2(19). pii: 95893
Immunity Infectious disease
Application of an Aptamer-Based Proteomics Assay (SOMAscan™) in Rat Cerebrospinal Fluid.
Simats A, et. al.
(2019) Methods Mol Biol. 2044:221-231
Application of large scale aptamer-based proteomic profiling to planned myocardial infarctions.
Jacob, J et. al.
(2018) Circulation 137(12): 1270-1277.
Application of Proteomics Profiling for Biomarker Discovery in Hypertrophic Cardiomyopathy.
Shimada YJ, et. al.
(2019) J Cardiovasc Transl Res. 2019 Dec;12(6):569-579
Aptamer-based multiplexed proteomic technology for biomarker discovery.
Gold, L et. al.
(2010) PLoS One 5(12): e15004.
Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis.
Nahid, P et. al.
(2014) Tuberculosis (Edinb) 94(3): 187-196.
Infectious disease
Aptamer-based proteomics of serum and plasma in acquired aplastic anemia.
Giudice, V et. al.
(2018) Exp Hematol 68: 38-50
Rare diseases
Aptamers and the RNA world, past and present.
Gold, L et. al.
(2012) Cold Spring Harb Perspect Biol 4(3).
Assessing the genetic correlations between blood plasma proteins and osteoporosis: a polygenic risk score analysis.
Liang, X et. al.
(2019) Calcif Tissue Int 104(2): 171-181
Osteoporosis Orthopedics
Assessment of variability in the SOMAscan assay.
Candia, J et. al.
(2017) Sci Rep 7(1):14248.
SomaScan technology
Atopic Dermatitis Endotypes Based on Allergen Sensitization, Reactivity to Staphylococcus aureus Antigens, and Underlying Systemic Inflammation.
Leonard A, et. al.
(2019) J Allergy Clin Immunol Pract. pii: S2213-2198(19)30719-6.
Inflammatory disease
Benefit of apabetalone on plasma proteins in renal disease.
Wasiak, S et. al.
(2018) Kidney International Reports 3(3): 711-721
Kidney disease
Cancer protein biomarker discovery based on nucleic acid aptamers.
Xiong H, et. al.
(2019) Int J Biol Macromol. 2019 Jul 1;132:190-202
Cerebrospinal fluid biomarkers link toxic astrogliosis and microglial activation to multiple sclerosis severity.
Masvekar, R et. al.
(2018) Mult Scler Relat Disord 28: 34-43
Cerebrospinal fluid protein changes in preeclampsia.
Ciampa, E et. al.
(2018) Hypertension 72(1): 219-226
Reproductive biology
Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy.
Gordin D, et. al.
(2019) Diabetes Care. 2019 Jul;42(7):1263-1273
Kidney disease Metabolic-disease
Circulating Biomarkers of Testosterone's Anabolic Effects on Fat-Free Mass.
Huang G, et. al.
Circulating proteomic signatures of chronological age.
Menni, C et. al.
(2015) J Gerontol A Biol Sci Med Sci 70(7): 809-816.
Classification of prostate cancer using a protease activity nanosensor library.
Dudani, JS et. al.
(2018) Proc Natl Acad Sci U S A 115(36): 8954-8959
Clinical validation of a protein biomarker panel for non-small cell lung cancer.
Jung, YJ et. al.
(2018) J Korean Med Sci 33(53): e342
Co-regulatory networks of human serum proteins link genetics to disease.
Emilsson, V et. al.
(2018) Science 361(6404): 769-773
Connecting genetic risk to disease end points through the human blood plasma proteome.
Suhre, K et. al.
(2017) Nat Commun 8: 14357.
SomaScan technology
Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand.
Gelinas, AD et. al.
(2014) J Biol Chem 289(12): 8720-8734.
SomaScan technology
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.
Zaghlool, SB et. al.
(2018) Hum Mol Genet 27(6): 1106-1121
Metabolic disease Respiratory
Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers.
Ochsner, UA et. al.
(2013) Diagn Microbiol Infect Dis 76(3): 278-285
Infectious disease
Development of a protein biomarker panel to detect non-small-cell lung cancer in Korea.
Jung, YJ et. al.
(2017) Clin Lung Cancer 18(2): e99-e107.
Diagnosis and prognosis-review of biomarkers for mesothelioma.
Sun, HH et. al.
(2017) Ann Transl Med 5(11): 244.
Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.
Thrush, AB et. al.
(2018) Int J Obes (Lond) 42(3): 353-362
Metabolic disease Osteoporosis-Orthopedics
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
Penn-Nicholson A, et. al.
(2019) PLoS Med. 2019 Apr; 16(4): e1002781
Infectious disease
Discovery and validation of a six-marker serum protein signature for the diagnosis of active pulmonary tuberculosis.
De Groote, MA et. al.
(2017) J Clin Microbiol 55(10): 3057-3071.
Infectious disease
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
Shi L, et. al.
(2019) Alzheimers Dement. 5. pii: S1552-5260(19)35118-0
Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy
Hathout Y, et. al.
(2019) Sci Rep. 2019 Aug 21;9(1):12167
Divergent roles for clusterin in lung injury and repair.
Habiel, DM et. al.
(2017) Sci Rep 7(1): 15444.
Fibrotic Disease Respiratory
Early identification of bronchopulmonary dysplasia using novel biomarkers by proteomic screening.
Forster, K et. al.
(2018) Am J Respir Crit Care Med 197(8): 1076-1080
Efficacy of individualised diets in patients with irritable bowel syndrome: a randomised controlled trial.
Ali A et. al.
(2017) BMJ Open Gastro 4(1): e000164.
Inflammatory disease
Elucidating novel serum biomarkers associated with pulmonary tuberculosis treatment.
De Groote, MA et. al.
(2013) PLoS One 8(4): e61002.
Infectious disease
Embracing proteins: structural themes in aptamer-protein complexes.
Gelinas, AD et. al.
(2016) Curr Opin Struct Biol 36: 122-132.
SomaScan technology
Endothelial microparticles and systemic complement activation in patients with chronic kidney disease.
Jalal, D et. al.
(2018) J Am Heart Assoc 7(14): e007818
Inflammatory disease Kidney-disease
Exosome swarms eliminate airway pathogens and provide passive epithelial immunoprotection through nitric oxide.
Nocera, AL et. al.
(2019) J Allergy Clin Immunol 143(4):1525-1535 e1521
Expanding the chemistry of DNA for in vitro selection.
Vaught, JD et. al.
(2010) J Am Chem Soc 132(12): 4141-4151.
SomaScan technology
Fatigue in sjorgen's syndrome: a search for biomarkers and treatment targets.
Bodewes, ILA et. al.
(2019) Front Immunol 10: 312.
Immunity Inflammatory disease
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Howson, JMM et. al.
(2017) Nat Genet 49(7): 1113-1119.
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome.
Suhre K, et. al.
Fit for the eye: aptamers in ocular disorders.
Drolet, DW et. al.
(2016) Nucleic Acid Ther 26(3): 127-146.
Other disease
GDF15 is a heart-derived hormone that regulates body growth.
Wang, T et. al.
(2017) EMBO Mol Med 9(8): 1150-1164
Cardiovascular Pediatric disease
Genetic architecture of the cardiovascular risk proteome.
Benson, MD et. al.
(2018) Circulation 137(11): 1158-1172
Genetic associations with micronutrient levels identified in immune and gastrointestinal networks.
Morine, MJ et. al.
(2014) Genes Nutr 9(4): 408
Metabolic disease
Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.
Sasayama, D et. al.
(2017) Hum Mol Genet 26(1): 44-51.
Genomic atlas of the human plasma proteome.
Sun, BB et. al.
(2018) Nature 558: 73-79
SomaScan technology
Guidelines for CSF Processing and Biobanking: Impact on the Identification and Development of Optimal CSF Protein Biomarkers.
Hok-A-Hin YS, et. al.
(2019) Methods Mol Biol. 2044:27-50
Neurological SomaScan technology
Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan.
Santos-Parker, JR et. al.
(2018) J Appl Physiol (1985) 125(5): 1646-1659
Harnessing the power of proteomics to assess drug safety and guide clinical trials.
Lam, MPY et. al.
(2018) Circulation 137(10): 1011-1014
High-content affinity-based proteomics: unlocking protein biomarker discovery.
Brody, EN et. al.
(2010) Expert Rev Mol Diagn 10(8): 1013-1022.
High-resolution molecular discrimination by RNA.
Jenison, RD et. al.
(1994) Science 263(5152): 1425-1429.
High-throughput characterization of blood serum proteomics of IBD patients with respect to aging and genetic factors.
Di Narzo, AF et. al.
(2017) PLoS Genet 13(1): e1006565
Aging Inflammatory disease
Highly multiplexed proteomic analysis of quantiferon supernatants to identify biomarkers of latent tuberculosis infection.
De Groote, MA et. al.
(2017) J Clin Microbiol 55(2): 391-402.
Infectious disease
Human PAH is characterized by a pattern of lipid-related insulin resistance.
Hemnes, AR et. al.
(2019) JCI Insight 4(1).
Metabolic disease Respiratory
Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis.
Wermuth, PJ et. al.
(2018) Rheumatology (Oxford) 57(10): 1698-1706
Identification of pathway-specific serum biomarkers of response to glucocorticoid and infliximab treatment in children with inflammatory bowel disease.
Heier, CR et. al.
(2016) Clin Transl Gastroenterol 7(9): e192.
Inflammatory disease Pediatric-disease
Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan.
Fong TG, et. al.
(2019) Ann Surg. 2019 Mar 26. doi: 10.1097
Aging Inflammatory disease
Identification of serum protein biomarkers for utrophin based DMD therapy.
Guiraud, S et. al.
(2017) Sci Rep 7: 43697.
Muskuloskeletal Pediatric disease
Identification of unique proteomic signatures in allergic and non-allergic skin disease.
Wang, J et. al.
(2017) Clin Exp Allergy 47(11): 1456-1467
Inflammatory disease
Improved preparation of 2 M triethylammonium bicarbonate.
Carlson, M et. al.
(2015) Green Chem Lett Rev 8(3-4): 37-39.
SomaScan technology
Improving probes for super-resolution.
Moore, RP et. al.
(2018) Nat Methods 15(9): 659-660
SomaScan technology
Increased cerebrospinal fluid fibrinogen in major depressive disorder.
Hattori, K et. al.
(2015) Sci Rep 5: 11412.
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation.
Kollar, B et. al.
(2018) Sci Rep 8(1): 14915
Inflammatory disease
Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides.
Wolk, SK et. al.
(2015) Nucleic Acids Res 43(19): 9107-9122.
SomaScan technology
Influenza a virus-triggered autophagy decreases the pluripotency of human-induced pluripotent stem cells.
Zahedi-Amiri A, et. al.
(2019) Cell Death Dis. 2019 May; 10(5): 337
Infectious disease Reproductive-biology
Integrative omics: harnessing the proteome to maximize the potential of the genome.
McGarrah, RW et. al.
(2018) Circulation 137(11): 1173-1175
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
Xie, Y et. al.
(2013) EMBO Rep 14(12): 1120-1126.
Oncology SomaScan technology
Interleukin 1 receptor-like 1 protein (ST2) is a potential biomarker for cardiomyopathy in Duchenne muscular dystrophy.
Anderson, J et. al.
(2017) Pediatr Cardiol 38(8): 1606-1612.
Cardiovascular Neurological Pediatric disease
Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA.
Zimmermann, GR et. al.
(1997) Nat Struct Biol 4(8): 644-649.
SomaScan technology
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.
Lertudomphonwanit, C et. al.
(2017) Sci Transl Med 9(417): eaan8462
Pediatric disease
Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy.
Hathout, Y et. al.
(2015) Proc Natl Acad Sci U S A 112(23): 7153-7158.
Muskuloskeletal Pediatric disease
Let's get specific: the relationship between specificity and affinity.
Eaton, BE et. al.
(1995) Chem Biol 2(10): 633-638.
SomaScan technology
Life's simple measures: unlocking the proteome.
Brody, E et. al.
(2012) J Mol Biol 422(5):595-606.
Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.
Lukjanenko, L et. al.
(2016) Nat Med 22(8): 897-905.
Aging Muskuloskeletal
Metabolic and proteomic signatures of hypoglycemia in type 2 diabetes.
Halama, A et. al.
(2018) Diabetes Obes Metab., Diabetes Obes Metab. 2018 Dec 7. doi: 10.1111
Metabolic disease
Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome.
Depner CM et. al.
(2018) Proc Natl Acad Sci U S A 115(23): E5390-E5399
Metabolic disease
Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging.
Strauss, S et. al.
(2018) Nat Methods 15(9): 685-688
SomaScan technology
Molecular-based diagnosis of multiple sclerosis and its progressive stage.
Barbour, C et. al.
(2017) Ann Neurol 82(5): 795-812.
Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjogren's syndrome.
Tasaki, S et. al.
(2017) Ann Rheum Dis 76(8): 1458-1466.
Non-helical DNA triplex forms a unique aptamer scaffold for high affinity recognition of nerve growth factor.
Jarvis, TC et. al.
(2015) Structure 23(7): 1293-1304.
SomaScan technology
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
Vilar-Gomez, E et. al.
(2018) J Hepatol 68(2): 305-315.
Fibrotic Disease Inflammatory-disease Metabolic-disease
Novel application of aptamer proteomic analysis in cystic fibrosis bronchoalveolar lavage fluid.
DeBoer, EM et. al.
(2018) Proteomics Clin Appl: e1800085
Rare diseases
Osteitis is associated with dysregulated pro-osteoblastic activity in patients with nasal polyps.
Wu, D et. al.
(2019) Laryngoscope 129(3): E102-E109
Exosomes Osteoporosis Orthopedics
Pharmacokinetic properties of DNA aptamers with base modifications.
Gupta, S et. al.
(2017) Nucleic Acid Ther 27(6): 345-353.
SomaScan technology
Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia.
Mulla CM, et. al.
(2019) Obes Surg. 2019 Jul;29(7):2092-2099
Metabolic disease
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study.
Rhodes, CJ et. al.
(2017) Lancet Respir Med 5(9): 717-726
Cardiovascular Rare diseases Respiratory
Plasma proteome in multiple sclerosis disease progression.
Malekzadeh A, et. al.
(2019) Ann Clin Transl Neurol. 2019 Sep;6(9):1582-1594
Plasma proteomic signature of age in healthy humans.
Tanaka, T et. al.
(2018) Aging Cell 17(5): e12799
Plasma proteomics identifies a 'chemokine storm' in idiopathic multicentric Castleman disease.
Pierson, SK et. al.
(2018) Am J Hematol 93(7): 902-912
Inflammatory disease Rare-diseases
Practical synthesis of cytidine-5-carboxamide-modified nucleotide reagents.
Rohloff, JC et. al.
(2015) Nucleosides Nucleotides Nucleic Acids 34(3): 180-198.
SomaScan technology
Probing the virtual proteome to identify novel disease biomarkers.
Mosley, JD et. al.
(2018) Circulation 138(22): 2469-2481
Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator.
Carayol, J et. al.
(2017) Nat Commun 8(1): 2084
Metabolic disease
Protein signature of lung cancer tissues.
Mehan, MR et. al.
(2012) PLoS One 7(4): e35157.
Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study.
Dubin, RF et. al.
(2018) PLoS One 13(12): e0208042
Cardiovascular Kidney disease
Proteomic profiles associated with early echocardiogram evidence of pulmonary vascular disease in preterm infants.
Wagner, BD et. al.
(2017) Am J Respir Crit Care Med 197(3): 394-397
Cardiovascular Pediatric disease
Proteomic profiles in advanced age-related macular degeneration using an aptamer-based proteomic technology.
Lynch, AM et. al.
(2019) Transl Vis Sci Technol 8(1): 14
Aging Other disease
Proteomic profiling identifies novel circulating markers associated with bronchiectasis in cystic fibrosis.
DeBoer, EM et. al.
(2017) Proteomics Clin Appl 11(9-10).
Pediatric disease Respiratory
Proteomic study of hepatocellular carcinoma using a novel modified aptamer-based array (SOMAscan) platform.
Qiao, Z et. al.
(2017) Biochim Biophys Acta 1865(4): 434-443.
Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan‚Ñ¢) platform.
Webber, J et. al.
(2014) Mol Cell Proteomics 13(4): 1050-1064.
Exosomes Oncology
Proteomics and diagnostics: Let's get specific, again.
Zichi, D et. al.
(2008) Curr Opin Chem Biol 12(1): 78-85.
SomaScan technology
Proteomics in gastroparesis: Unique and overlapping protein signatures in diabetic and idiopathic gastroparesis.
Grover M, et. al.
(2019) Am J Physiol Gastrointest Liver Physiol. 2019 Sep 4. doi: 10.1152
Immunity Metabolic disease
Proteomics profiling and risk of new-onset atrial fibrillation: Framingham Heart Study.
Ko, D et. al.
(2019) J Am Heart Assoc 8(6): e010976
Pulmonary Aptamer Signatures in Children's Interstitial and Diffuse Lung Diseases.
Deterding RR, et. al.
(2019) Am J Respir Crit Care Med. doi: 10.1164
Pediatric disease Respiratory
Rapid histochemistry using slow off-rate modified aptamers with anionic competition.
Gupta, S et. al.
(2011) Appl Immunohistochem Mol Morphol 19(3): 273-278.
SomaScan technology
readat: an R package for reading and working with SomaLogic ADAT files.
Cotton, RJ et. al.
(2016) BMC Bioinformatics 17(1): 201.
Reproducibility and variability of protein analytes measured using a multiplexed modified aptamer assay.
Tin, A et. al.
(2019) J Appl Lab Med. 2019 Jul;4(1):30-39
Respiratory mucosal proteome quantification in human influenza infections.
Marion, T et. al.
(2016) PLoS One 11(4): e0153674.
Infectious disease
Scanning into the future: the promise of SOMAScan technology for kidney disease.
Coca, SG
(2018) Kidney Int Rep 3(5): 1020-1022
Kidney disease
Selection of DNA aptamers with two modified bases.
Gawande, BN et. al.
(2017) Proc Natl Acad Sci U S A 114(11): 2898-2903.
SomaScan technology
SELEX: How it happened and where it will go.
Gold, L
(2015) J Mol Evol 81(5-6): 140-143.
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.
Scriba, TJ et. al.
(2017) PLoS Pathog 13(11): e1006687.
Infectious disease
Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis.
Rice, LM et. al.
(2018) Arthritis Res Ther 20(1): 185
Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.
Hathout, Y et. al.
(2016) Sci Rep 6: 31727.
Inflammatory disease Pediatric-disease
Serum proteomic assessment of the progression of fracture healing.
Hussein, AI et. al.
(2018) J Orthop Res 36(4): 1153-1163
Osteoporosis Orthopedics
Sexual dimorphism, age, and fat mass are key phenotypic drivers of proteomic signatures.
Curran, AM et. al.
(2017) J Proteome Res 16(11): 4122-4133.
Aging Metabolic disease
Six-SOMAmer index relating to immune, protease and angiogenic functions predicts progression in IPF.
Ashley, SL et. al.
(2016) PLoS One 11(8): e0159878.
Fibrotic Disease Respiratory
Specific capture and detection of Staphylococcus aureus with high-affinity modified aptamers to cell surface components.
Baumstummler, A et. al.
(2014) Lett Appl Microbiol 59(4): 422-431.
Infectious disease
Sperm cell purification from mock forensic swabs using SOMAmerTM affinity reagents.
Katilius E et. al.
(2018) Forensic Sci Int Genet 35: 9-13
SomaScan technology
Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma.
Rossios, C et. al.
(2018) J Allergy Clin Immunol 141(2): 560-570.
Stability and reproducibility of proteomic profiles measured with an aptamer-based platform.
Kim, CH et. al.
(2018) Sci Rep 8(1): 8382
SomaScan technology
Stress Hyperglycemia in Critically Ill Patients: Insight Into Possible Molecular Pathways.
Bar-Or D, et. al.
(2019) Front Med (Lausanne). 2019; 6: 54
Metabolic disease Neurological
Systematic selection of modified aptamer pairs for diagnostic sandwich assays.
Ochsner, UA et. al.
(2014) Biotechniques 56(3): 125-128, 130, 132-133.
Cardiovascular Infectious disease SomaScan-technology
The impact of the glomerular filtration rate on the human plasma proteome.
Christensson, A et. al.
(2018) Proteomics Clin Appl 12(3): e1700067
Kidney disease
The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology.
Westwood, S et. al.
(2017) Alzheimers Res Ther 9(1): 31.
Aging Metabolic disease
The maternal plasma proteome changes as a function of gestational age in normal pregnancy: a longitudinal study.
Romero, R et. al.
(2017) Am J Obstet Gynecol 217(1):67 e61-67 e21.
Reproductive biology
The prediction of late-onset preeclampsia: Results from a longitudinal proteomics study.
Erez, O et. al.
(2017) PLoS One 12(7): e0181468.
Reproductive biology
The relationship of circulating proteins in early pregnancy with preterm birth.
Lynch, AM et. al.
(2016) Am J Obstet Gynecol 214(4): 517 e511-518.
Reproductive biology
The relationship of novel plasma proteins in the early neonatal period with retinopathy of prematurity.
Lynch, AM et. al.
(2016) Invest Ophthalmol Vis Sci 57(11): 5076-5082.
Pediatric disease
Tracking disease progression non-invasively in Duchenne and Becker muscular dystrophies.
Spitali, P et. al.
(2018) J Cachexia Sarcopenia Muscle 9(4): 715-726
Muskuloskeletal Pediatric disease
Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation.
Sullivan, KD et. al.
(2017) Sci Rep 7(1): 14818.
Rare diseases
Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Davies, DR et. al.
(2012) Proc Natl Acad Sci U S A 109(49): 19971-19976
SomaScan technology
Validation of a blood protein signature for non-small cell lung cancer.
Mehan, MR et. al.
(2014) Clin Proteomics 11(1): 32.
Vero cell proteomic changes induced by Zika virus infection.
Glover, KKM et. al.
(2018) Proteomics 19(4): e1800309
Infectious disease Neurological
Vitamin B12 deficiency and impaired expression of amnionless during aging.
Pannerec, A et. al.
(2017) J Cachexia Sarcopenia Muscle 9(1): 41-52.
Zika virus infection disrupts astrocytic proteins involved in synapse control and axon guidance.
Sher et. al.
(2019) Front Microbiol. 2019 Mar 26;10:596
Infectious disease Neurological